Do not use Panadol Extra with Optizorb: - If you are allergic to paracetamol, caffeine or hydroxybenzoates - If using other medicines containing paracetamol or caffeine - For children below age 12 - For more than 48 hours for children aged 12-17 except on medical advice - For more than a few days at a time in adults except on medical advice - If pregnant, except on medical advice - If any of the seals on this packaging are broken - If the package use-by date has expired - Until you read the enclosed leaflet carefully Ask a doctor before use - If you have liver or kidney problems - If you are taking warfarin (a medicine used to thin the blood) - If you are breastfeeding Stop use and see your doctor immediately if You have an allergic skin reaction, shortness of breath or wheezing after taking Panadol. These reactions are very rare."