1.Clean and dry the skin before use, ensuring blister area is free from creams and oils. 2.Remove the bottom paper, avoiding touching the adhesive side. 3.Apply plaster firmly over the blister ensuring the edges are well smoothed down. 4. leave in place until it starts to detach (Note: May stay in place for several days). 5.To remove plaster, Do Not Pull Upwards, but slowly stretch along the skin.